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Alarming Study: Smoking Causes Brain Shrinkage It Sounds Bad, and It Is Bad Nicotine and the Brain: How Nicotine Affects the Brain HealthyPlace Study shows smoking likely leads to brain shrinkage 26 Health Effects of Smoking on Your Body What Happens When You Smoke? Cigarettes contain nicotine, tar, and carbon monoxide. Short term effects: Increased heart rate Higher blood pressure Reduced oxygen Long term effects: Lung cancer
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